Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi, Nobuhiro Morone, Atsutaka Minagawa, Bo Wang, Ikuhiro Okamoto, Tomonori Nakamura, Yoji Kojima, Chizuru Iwatani, Hideaki Tsuchiya, Belinda Kaswandy, Eiji Kondoh, Shin Kaneko, Knut Woltjen, Mitinori Saitou, Takuya Yamamoto, Masaki Mandai, Yasuhiro Takashima
Capturing human trophoblast development with naive pluripotent stem cells in vitro
Cell Stem Cell 28(6), 1023-1039.e13, 2021年4月, 10.1016/j.stem.2021.03.013 [
]
Yasuhiro Kazuki, Narumi Uno, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Yuwna Yakura, Chiaki Sawada, Shuta Takata, Masaki Sugawara, Yuichi Nagashima, Akane Okada, Masaharu Hiratsuka, Mitsuhiko Osaki, Giulia Ferrari, Francesco Saverio Tedesco, Satoshi Nishikawa, Ken Fukumoto, Shin-Ichiro Takayanagi, Atsushi Kunisato, Shin Kaneko, Mitsuo Oshimura, Kazuma Tomizuka
Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling.
Molecular therapy. Nucleic acids 23, 629-639, 2021年3月5日, 10.1016/j.omtn.2020.12.012 [
33552683]
Shoichi Iriguchi, Yutaka Yasui, Yohei Kawai, Suguru Arima, Mihoko Kunitomo, Takayuki Sato, Tatsuki Ueda, Atsutaka Minagawa, Yuta Mishima, Nariaki Yanagawa, Yuji Baba, Yasuyuki Miyake, Kazuhide Nakayama, Maiko Takiguchi, Tokuyuki Shinohara, Tetsuya Nakatsura, Masaki Yasukawa, Yoshiaki Kassai, Akira Hayashi, Shin Kaneko
A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy
Nature Communications 12(1), -, 2021年1月18日, 10.1038/s41467-020-20658-3 [
]
Masazumi Waseda, Shin Kaneko
Podoplanin as an Attractive Target of CAR T Cell Therapy
Cells 9(9), 1971-1971, 2020年8月26日, 10.3390/cells9091971 [
]
Tatsuki Ueda, Ayako Kumagai, Shoichi Iriguchi, Yutaka Yasui, Tadayo Miyasaka, Kengo Nakagoshi, Kazuki Nakane, Keigo Saito, Mari Takahashi, Aki Sasaki, Shinsuke Yoshida, Naoko Takasu, Hiroshi Seno, Yasushi Uemura, Koji Tamada, Tetsuya Nakatsura, Shin Kaneko
Non–clinical efficacy, safety and stable clinical cell processing of induced pluripotent stem cell-derived anti–glypican-3 chimeric antigen receptor-expressing natural killer/innate lymphoid cells
Cancer Science 111(5), 1478-1490, 2020年5月1日, 10.1111/cas.14374 [
32133731]
Hiroaki Mashima, Rong Zhang, Tsuyoshi Kobayashi, Yuichiro Hagiya, Hirotake Tsukamoto, Tianyi Liu, Tatsuaki Iwama, Masateru Yamamoto, Chiahsuan Lin, Ryusuke Nakatsuka, Yuta Mishima, Noriko Watanabe, Takashi Yamada, Satoru Senju, Shin Kaneko, Alimjan Idiris, Tetsuya Nakatsura, Hideki Ohdan, Yasushi Uemura
Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response
OncoImmunology 9(1), 1814620-1814620, 2020年1月1日, 10.1080/2162402x.2020.1814620 [
]
Nobuhiro Tsuchiya, Rong Zhang, Tatsuaki Iwama, Norihiro Ueda, Tianyi Liu, Minako Tatsumi, Yutaka Sasaki, Ranmaru Shimoda, Yuki Osako, Yu Sawada, Yosuke Kubo, Azusa Miyashita, Satoshi Fukushima, Zhao Cheng, Ryo Nakaki, Keiyo Takubo, Seiji Okada, Shin Kaneko, Hironobu Ihn, Tsuneyasu Kaisho, Yasuharu Nishimura, Satoru Senju, Itaru Endo, Tetsuya Nakatsura, Yasushi Uemura
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.
Cell reports 29(1), 162-175, 2019年10月1日, 10.1016/j.celrep.2019.08.086 [
31577946]
Huaigeng Xu, Bo Wang, Miyuki Ono, Akihiro Kagita, Kaho Fujii, Noriko Sasakawa, Tatsuki Ueda, Peter Gee, Misato Nishikawa, Masaki Nomura, Fumiyo Kitaoka, Tomoko Takahashi, Keisuke Okita, Yoshinori Yoshida, Shin Kaneko, Akitsu Hotta
Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility.
Cell stem cell 24(4), 566-578, 2019年4月4日, 10.1016/j.stem.2019.02.005 [
30853558]
Yu-suke Torisawa, Yuta Mishima, Shin Kaneko
Developing thymus-on-a-chip and cancer-on-a-chip for cancer immunotherapy
Impact 2019(2), 33-35, 2019年3月18日, 10.21820/23987073.2019.2.33 [
]
Methods in Molecular Biology, Yasumichi Hitoshi, Shin Kaneko
In Vitro Differentiation of T Cell: From Human iPS Cells in Feeder-Free Condition
Methods in Molecular Biology 2048, 77-80, 2019年, 10.1007/978-1-4939-9728-2_8 [
31396931]
Iriguchi S, Kaneko S
Toward the development of true “off-the-shelf” synthetic T-cell immunotherapy.
Cancer science 110(1), 16-22, 2019年1月, 10.1111/cas.13892 [
30485606]
Atsutaka Minagawa, Toshiaki Yoshikawa, Masaki Yasukawa, Akitsu Hotta, Mihoko Kunitomo, Shoichi Iriguchi, Maiko Takiguchi, Yoshiaki Kassai, Eri Imai, Yutaka Yasui, Yohei Kawai, Rong Zhang, Yasushi Uemura, Hiroyuki Miyoshi, Mahito Nakanishi, Akira Watanabe, Akira Hayashi, Kei Kawana, Tomoyuki Fujii, Tetsuya Nakatsura, Shin Kaneko
Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy.
Cell stem cell 23(6), 850-858, 2018年12月6日, 10.1016/j.stem.2018.10.005 [
30449714]
Suji Lee, Ji Young Huh, David M Turner, Soohyeon Lee, James Robinson, Jeremy E Stein, Sung Han Shim, Chang Pyo Hong, Myung Seo Kang, Masato Nakagawa, Shin Kaneko, Mahito Nakanishi, Mahendra S Rao, Andreas Kurtz, Glyn N Stacey, Steven G E Marsh, Marc L Turner, Jihwan Song
Repurposing the Cord Blood Bank for Haplobanking of HLA-Homozygous iPSCs and Their Usefulness to Multiple Populations.
Stem cells (Dayton, Ohio) 36(10), 1552-1566, 2018年10月, 10.1002/stem.2865 [
30004605]
Kei Higaki, Masako Hirao, Ai Kawana-Tachikawa, Shoichi Iriguchi, Ayako Kumagai, Norihiro Ueda, Wang Bo, Sanae Kamibayashi, Akira Watanabe, Hiromitsu Nakauchi, Kazuo Suzuki, Shin Kaneko
Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA.
Molecular therapy. Nucleic acids 12, 793-804, 2018年9月7日, 10.1016/j.omtn.2018.07.017 [
30141412]
Norihiro Ueda, Yasushi Uemura, Rong Zhang, Shuichi Kitayama, Shoichi Iriguchi, Yohei Kawai, Yutaka Yasui, Minako Tatsumi, Tatsuki Ueda, Tian-Yi Liu, Yasutaka Mizoro, Chihiro Okada, Akira Watanabe, Mahito Nakanishi, Satoru Senju, Yasuharu Nishimura, Kiyotaka Kuzushima, Hitoshi Kiyoi, Tomoki Naoe, Shin Kaneko
Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response.
Stem cell reports 10(6), 1935-1946, 2018年6月5日, 10.1016/j.stemcr.2018.04.025 [
29805109]
Koichi Oshima, Norikazu Saiki, Michihiro Tanaka, Hiromi Imamura, Akira Niwa, Ayako Tanimura, Ayako Nagahashi, Akiyoshi Hirayama, Keisuke Okita, Akitsu Hotta, Shuichi Kitayama, Mitsujiro Osawa, Shin Kaneko, Akira Watanabe, Isao Asaka, Wataru Fujibuchi, Kohsuke Imai, Hiromasa Yabe, Yoshiro Kamachi, Junichi Hara, Seiji Kojima, Masaru Tomita, Tomoyoshi Soga, Takafumi Noma, Shigeaki Nonoyama, Tatsutoshi Nakahata, Megumu K Saito
Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.
Biochemical and biophysical research communications 497(2), 719-725, 2018年3月4日, 10.1016/j.bbrc.2018.02.139 [
29462620]
Norihiro Ueda, Rong Zhang, Minako Tatsumi, Tian-Yi Liu, Shuichi Kitayama, Yutaka Yasui, Shiori Sugai, Tatsuaki Iwama, Satoru Senju, Seiji Okada, Tetsuya Nakatsura, Kiyotaka Kuzushima, Hitoshi Kiyoi, Tomoki Naoe, Shin Kaneko, Yasushi Uemura
BCR-ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells
Cellular and Molecular Immunology 15(1), 15-26, 2018年1月1日, 10.1038/cmi.2016.7 [
]
Radulovic Visnja, Van der, Garde Mark, Sigurdsson Valgardur, Zriwil Alya, Soboleva Svetlana, Quinn Ewa Sitnicka, Kaneko Shin, Miharada Kenichi
Junctional Adhesion Molecule 2 Intensifies T Lymphopoiesis of Hematopoietic Stem Cells By Facilitating Notch/Delta Signaling
王 博, 入口 翔一, 上田 樹, 上田 格弘, 南川 淳隆, 喜多山 秀一, 植村 靖史, 中面 哲也, 江藤 浩之, 堀田 秋津, 金子 新
iPS細胞技術を用いたT細胞治療療法のためのユニバーサルドナー細胞の作製
日本癌学会総会記事 76回(P), 2371-, , []
上田 樹, 入口 翔一, 河合 洋平, 南川 淳隆, 三好 浩之, 寺倉 精太郎, 植村 靖史, ウォルツェン・クヌート, 児玉 裕三, 玉田 耕治, 中面 哲也, 妹尾 浩, 金子 新
GPC3を標的としたiPS細胞由来CAR-T療法
日本癌学会総会記事 76回, P-1251, 2017年9月, []
